Publications

Recent Key Publications from the ADMIRE network

  • Johann Bauersachs, Frédéric Jaisser, Robert Toto. Mineralocorticoid Receptor Activation and Mineralocorticoid Receptor Antagonist Treatment in Cardiac and Renal Diseases. Hypertension. 2015;65:257-263.
  • Schwagerus E, Sladek S, Buckley ST, Armas-Capote N, de la Rosa DA, Harvey BJ, Fischer H, Illek B, Huwer H, Schneider-Daum N, Lehr CM, Ehrhardt C. Expression and function of the epithelial sodium channel δ-subunit in human respiratory epithelial cells in vitro.  Pflugers Archives: European Journal of Physiology. 2015 Feb 13. PMID: 25677639.
  • David G. Warnock, Kristina Kusche-Vihrog, Antoine Tarjus, Shaohu Sheng, Hans Oberleithner, Thomas R. Kleyman, Frederic Jaisser. Blood pressure and amiloride-sensitive sodium channels in vascular and renal cells. Nature Reviews Nephrology. 10, 146–157.2014.
  • Cristiana Catena, Nicolas Verheyen, Stefan Pilz, Elisabeth Kraigher-Krainer,Andreas Tomaschitz, Leonardo A. Sechi, Burkert Pieske. Plasma Aldosterone and Left Ventricular Diastolic Function in Treatment-Naïve Patients With Hypertension: Tissue-Doppler Imaging Study.  Hypertension.2015 Jun 23;65(6):1231-7. Epub 2015 Mar 23.
  • Cristiana Catena, MD, PhD, GianLuca Colussi, MD, Marion Url–Michitsch, MD, Francesca Nait, MD,Leonardo A. Sechi, MD. Subclinical carotid artery disease and plasma homocysteine levels in patients with hypertension. Journal of the American Society of Hypertension 9(3) (2015) 167–175
  • Urbanet R, Nguyen Dinh Cat A, Feraco A, Gravez B, El Mograhbi S, Sierra-Ramos C, Alvarez de la Rosa D, Quilliot D, Rossignol P, Venteclef N, Clement K, Fallo F, Touyz RM, Jaisser F.  Adipocyte mineralocorticoid receptor activation leads to metabolic syndrome and induction of Prostaglandin D2 Synthase. Hypertension, 2015. Jul;66(1):149-57.
  • Natalia Lopez-Andres, Faiez Zannad, Frederic Jaisser. Neutrophil Gelatinase Associated Lipocalin, a novel mineralocorticoid biotarget, mediates vascular pro-fibrotic effects of mineralocorticoids. Hypertension. 2015;66:158-166
  • Kusche-Vihrog K1, Tarjus A, Fels J, Jaisser F. The epithelial Na+ channel: a new player in the vasculature. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):143-8. 9.
  • Antoine Tarjus, Cristian Amador,Luis Michea,Frédéric Jaisser. Vascular mineralocorticoid receptor and blood pressure regulation. Current Opinion in Pharmacology, 2015
  • Fernandes-Rosa FL, Williams TA, Riester A, Steichen O, Beuschlein F, Boulkroun S, Strom TM, Monticone S, Amar L, Meatchi T, Mantero F, Cicala MV, Quinkler M, Fallo F, Allolio B, Bernini G, Maccario M, Giacchetti G, Jeunemaitre X, Mulatero P, Reincke M, Zennaro MC. Genetic spectrum and clinical correlates of somatic mutations in aldosterone-producing adenoma. Hypertension-2014-64; 354-361
  • Martínez-Martínez E , Cachofeiro V, Rousseau E, Álvarez V, Calvier L, Fernández-Celis A, Leroy C, Miana M, Jurado-López R, Briones AM, Jaisser F, Zannad F, Rossignol P, López-Andrés N. Interleukin-33/ST2 system attenuates aldosterone-induced adipogenesis and inflammation. Mol Cell Endocrinol. 2015 Aug 15;411:20-7.
  • Martínez-Martínez E1, López-Ándres N1, Jurado-López R1, Rousseau E1, Bartolomé MV1, Fernández-Celis A1, Rossignol P1, Islas F1, Antequera A1, Prieto S1, Luaces M1, Cachofeiro V2. Galectin-3 Participates in Cardiovascular Remodeling Associated With Obesity. Hypertension. 2015 Nov;66(5):961-9.
  • Tarjus A, Martínez-Martínez E, Amador C, Latouche C, El Moghrabi S, Berger T, Mak TW, Fay R, Farman N, Rossignol P, Zannad F, López-Andrés N, Jaisser F. Neutrophil Gelatinase-Associated Lipocalin, a Novel Mineralocorticoid Biotarget, Mediates Vascular Profibrotic Effects of Mineralocorticoids. Hypertension. 2015 Jul;66(1):158-66.
  • Martínez-Martínez E, Calvier L, Fernández-Celis A, Rousseau E, Jurado-López R, Rossoni LV, Jaisser F, Zannad F, Rossignol P, Cachofeiro V, López-Andrés N. Galectin-3 blockade inhibits cardiac inflammation and fibrosis in experimental hyperaldosteronism and hypertension. Eur J Heart Fail. 2015 Aug;17(8):764-71. doi: 10.1002/ejhf.312. Epub 2015 Jun 30.
  • Heymans S, González A, Pizard A, Papageorgiou AP, López-Andrés N, Jaisser F, Thum T, Zannad F, Díez J. Searching for new mechanisms of myocardial fibrosis with diagnostic and/or therapeutic potential. Hypertension. 2015 Oct;66(4):767-75. doi: 0.1161/HYPERTENSIONAHA.115.05876.
  • Martínez-Martínez E1, Calvier L2, Rossignol P2, Rousseau E2, Fernández-Celis A1, Jurado-López R3, Laville M4, Cachofeiro V3, López-Andrés N1,2. Galectin-3 inhibition prevents adipose tissue remodelling in obesity. Int J Obes (Lond). 2016 Feb 8. doi: 10.1038/ijo.2016.19.
  • Bauersachs J, Jaisser F, Toto R. Mineralocorticoid receptor activation and mineralocorticoid receptor antagonist treatment in cardiac and renal diseases. Hypertension. 2015 Feb;65(2):257-63. doi: 10.1161/HYPERTENSIONAHA.114.04488.
  • Montezano AC, Dulak-Lis M, Tsiropoulou S, Harvey A, Briones AM, Touyz RM. Oxidative stress and human hypertension: vascular mechanisms, biomarkers, and novel therapies. Can J Cardiol. 2015 May;31(5):631-41. doi: 10.1016/j.cjca.2015.02.008. Epub 2015 Feb 14.
  • Aguado A, Fischer T, Rodríguez C, Manea A, Martínez-González J, Touyz RM, Hernanz R, Alonso MJ, Dixon DA, Briones AM, Salaices M. Hu antigen R is required for NOX-1 but not NOX-4 regulation by inflammatory stimuli in vascular smooth muscle cells. J Hypertens. 2016 Feb;34(2):253-65.
  • Jiménez-Canino R, Lorenzo-Díaz F, Jaisser F, Farman N, Giraldez T, Alvarez de la Rosa D. Histone deacetylase 6-controlled Hsp90 acetylation significantly alters mineralocorticoid receptor subcellular dynamics but not its transcriptional activity. Endocrinology. 2016 Apr 21:en20152055.
  • Urbanet R, Nguyen Dinh Cat A, Feraco A, Venteclef N, El Mogrhabi S, Sierra-Ramos C, Alvarez de la Rosa D, Adler GK, Quilliot D, Rossignol P, Fallo F, Touyz RM, Jaisser F. Adipocyte Mineralocorticoid Receptor Activation Leads to Metabolic Syndrome and Induction of Prostaglandin D2 Synthase. Hypertension. 2015 Jul;66(1):149-57. doi: 10.1161/HYPERTENSIONAHA.114.04981. Epub 2015 May 11.
  • Barrera-Chimal J, Pérez-Villalva R, Ortega JA, Sánchez A, Rodríguez-Romo R, Durand M, Jaisser F, Bobadilla NA. Mild ischemic injury leads to long-term alterations in the kidney: amelioration by spironolactone administration. Int J Biol Sci. 2015 Jun 6;11(8):892-900. doi: 10.7150/ijbs.11729.
  • Barrera-Chimal J, Bobadilla NA, Jaisser F.Mineralocorticoid Receptor Antagonism: A Promising Therapeutic Approach to Treat Ischemic AKI. Nephron. 2016 Mar 19.
  • Mammi C, Marzolla V, Armani A, Feraco A, Antelmi A, Maslak E, Chlopicki S, Cinti F, Hunt H, Fabbri A, Caprio M. A novel combined glucocorticoid-mineralocorticoid receptor selective modulator markedly prevents weight gain and fat mass expansion in mice fed a high-fat diet. Int J Obes (Lond). 2016 Feb 2. doi: 10.1038/ijo.2016.13. [Epub ahead of print] PubMed PMID: 26830012.
  • Reihill JA, Walker B, Hamilton RA, Ferguson TE, Elborn JS, Stutts MJ, Harvey BJ, Saint-Criq V, Hendrick SM, Martin SL. Inhibition of Protease-ENaC Signaling Improves Mucociliary Function in Cystic Fibrosis Airways. Am J Respir Crit Care Med. 2016 Mar 25. [Epub ahead of print] PubMed PMID: 27014936
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